解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND AND PURPOSE:Cerebral infarction in sickle cell disease is associated with arterial narrowing or occlusions of intracranial arteries. Primary stroke prevention would be feasible if a noninvasive screening test could be developed to detect intracranial disease in patients before symptoms develop. METHODS:To d...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.8.1073
更新日期:1992-08-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The pressure-flow relation has been characterized in normal cerebrum, but it has not been studied in cerebrum dependent on collateral flow. The purpose of this investigation was to examine the relation between systemic pressure, regional cerebral blood flow, and middle cerebral artery branch pres...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.7.988
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Mild hypothermia has been shown to ameliorate neuronal damage due to cerebral ischemia. In our study, the influence of mild-to-moderate hypothermia was examined in a rabbit model of focal cerebral ischemia. METHODS:After 4 hours of permanent ischemia induced by occlusion of the anterior and midd...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.6.889
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We evaluated the impact of lifestyle factors on the risk of ischemic stroke. METHODS:We used a nested case-control design. The cases comprised 163 persons (median age 69 years) admitted to a stroke unit and diagnosed with acute cerebral infarction. All cases had earlier participated in the North...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.6.829
更新日期:1992-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Treatment with the ketone body precursor 1,3-butanediol has been suggested to ameliorate hypoxic/ischemic brain damage. Butanediol could provide an alternative energy substrate for the brain, thereby decreasing the amount of glycolytically produced lactate. Hyperglycemia aggravates brain damage a...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.5.719
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:There is little reported of the safety and efficacy of high-dose intravenous recombinant tissue plasminogen activator (alteplase) in combination with heparin anticoagulation in patients presenting with acute ischemic stroke. METHODS:Thirty-two patients with severe hemispheric stroke syndrome cau...
journal_title:Stroke
pub_type: 临床试验,杂志文章
doi:10.1161/01.str.23.5.646
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Conventional diets may cause hyperglycemia in patients with neurological injuries. The purpose of this study was to examine the effect on the severity of cerebral infarction of replacing carbohydrates as the primary dietary source of nonprotein calories. METHODS:Sixty-nine Long-Evans rats were e...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.4.564
更新日期:1992-04-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Computed tomography is now routinely used in many hospitals to investigate cerebrovascular disease. The purpose of our prospective study was to determine whether cranial computed tomography in connection with neurological assessment was useful in prognostic evaluation of survival after acute stro...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.4.506
更新日期:1992-04-01 00:00:00
abstract::The frequency of angiographically defined asymptomatic CAD in patients with carotid disease is 40%. Although the prognosis of patients with asymptomatic 1-vessel or 2-vessel CAD is good (annual cardiac mortality rate less than 2%), the prognosis of asymptomatic 3-vessel disease or left main CAD is substantially less f...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.str.23.3.433
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Our investigation sought to determine whether neonatal brain ischemic vascular and metabolic effects were altered by repeated episodes of ischemia. METHODS:We studied twelve piglets using in vivo magnetic resonance spectroscopy to obtain multiple, simultaneous measurements of cerebral blood flow...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.3.380
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Lacunes are thought to occur in patients with hypertension or diabetes mellitus as a result of small-vessel disease. This study evaluated the importance of other stroke mechanisms in a population of patients with lacunar infarction. METHODS:We evaluated 108 consecutive patients with a lacune in ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.3.325
更新日期:1992-03-01 00:00:00
abstract::There is a strong link between antiphospholipid antibodies and stroke. Retrospective studies indicate that these patients are generally young, often have had prior thrombotic events including stroke, frequently complain of headaches, and often experience amaurosis fugax. Cardiac valvular lesions, particularly involvin...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The aim of this study is to report on the use of transcranial Doppler ultrasonography as a noninvasive diagnostic monitoring tool during local intra-arterial thrombolysis in a patient with acute embolic occlusion of the middle cerebral artery. CASE DESCRIPTION:We describe a 41-year-old woman wit...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.2.284
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The reproducibility of duplex scan measures of carotid atherosclerosis was evaluated as part of a study assessing the prevalence of carotid disease in elderly adults. METHODS:Doppler measures of blood flow velocity were used to evaluate disease severity, and extent of carotid plaque was scored f...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.2.215
更新日期:1992-02-01 00:00:00
abstract:BACKGROUND:Improved neurological outcome with postarrest hypertensive hemodilution in an earlier study could be the result of more homogeneous cerebral perfusion and improved O2 delivery. We explored global, regional, and local cerebral blood flow by stable xenon-enhanced computed tomography and global cerebral metabol...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.1.45
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Following our treatment of a patient with hypoglycemia-induced brain stem symptoms, we examined the possible mechanisms for hypoglycemia presenting as basilar artery disease. CASE DESCRIPTION:We describe a patient who had progressive brain stem symptoms due to a diet-induced hypoglycemia initial...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.1.112
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Impaired rheological properties of as well as cytotoxic substances produced by granulocytes may contribute to tissue damage in acute ischemic stroke. To assess changes in the properties of circulating granulocytes, we measured their adhesion, deformability, and superoxide generation in the first ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.23.1.33
更新日期:1992-01-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The goal of this study was to determine the alterations in contractile and dilatory responses and ultrastructure of the feline middle cerebral artery after hemorrhagic hypotension. METHODS:In the sodium pentobarbital anesthetized cats, a steady 50 mm Hg level of hypotension was reached by bleedi...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.12.1541
更新日期:1991-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The purpose of the present study is to determine the effect of mild hypothermia on the synthesis of ubiquitin, an important protein for maintenance of cell viability, in the hippocampal neurons following transient cerebral ischemia. METHODS:Transient ischemia was induced by occluding both common...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.12.1574
更新日期:1991-12-01 00:00:00
abstract:BACKGROUND AND PURPOSE:We sought to determine the effects of aging on regional cerebral blood flow and ischemic brain damage in transient cerebral ischemia in rats. METHODS:Five adult (5-6 months) and five aged (18-22 months) female spontaneously hypertensive rats were subjected to 20 minutes of bilateral carotid occl...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.11.1414
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND:To judge the efficacy of new, putative stroke therapies, we need a method to measure neurological deficit accurately in groups of patients before and after treatment. No single measurement technique has yet proven to be universally acceptable, but one approach is the use of rating instruments that summarize ...
journal_title:Stroke
pub_type: 杂志文章,评审
doi:10.1161/01.str.22.11.1345
更新日期:1991-11-01 00:00:00
abstract:BACKGROUND AND PURPOSE:The purpose of the study is to compare the reliability of the Barthel activities of daily living score, which assesses disability, with the Rankin scale, which assesses handicap, and to determine their mutual agreement. METHODS:Fifty patients with stroke of varying severity were identified by a ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.10.1242
更新日期:1991-10-01 00:00:00
abstract::Although the blood flow tracer hexamethylpropyleneamine oxime is now widely used for cerebral blood flow mapping using single-photon emission computed tomography, its uptake into acutely ischemic brain has not been well studied. We performed a double-label autoradiographic study in which 99mTc-hexamethylpropyleneamine...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.10.1284
更新日期:1991-10-01 00:00:00
abstract::We studied the pattern and outcome of strokes in 200 Saudi patients. Cerebral infarction constituted 87% of strokes, subarachnoid hemorrhage 4.5%, cerebral hemorrhage 6.5%, and venous infarction 2%. The vessel most commonly involved was part or all of the middle cerebral artery, constituting 52% (90) of the 174 arteri...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.9.1173
更新日期:1991-09-01 00:00:00
abstract::We investigated the temporal threshold for focal cerebral infarction in the spontaneously hypertensive rat. The right middle cerebral artery and common carotid artery were occluded for 0, 1, 2, 3, 4, or 24 hours, and all the animals were sacrificed 24 hours after the onset of ischemia. Cortical infarct volumes and ede...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.8.1032
更新日期:1991-08-01 00:00:00
abstract::To evaluate the role of platelet function in the pathogenesis of cerebral vasospasm, we compared sequential changes of platelet aggregability and beta-thromboglobulin and thromboxane B2 concentrations in blood samples from the internal jugular and peripheral vein of 13 patients with aneurysmal subarachnoid hemorrhage....
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.7.854
更新日期:1991-07-01 00:00:00
abstract::We examined the 21-aminosteroid U74006F, a potent inhibitor of lipid peroxidation, for potential neuroprotective effects in a canine model of complete cerebral ischemia. Two 1.5-mg/kg boluses were administered to six dogs, the first bolus 15 minutes prior to a 12-minute episode of complete cerebral ischemia and the se...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.7.902
更新日期:1991-07-01 00:00:00
abstract::Previous studies suggest that rheological changes associated with ischemia may produce postischemic hypoperfusion. We tested whether intracarotid or intravenous infusions of saline improve neurological outcome from incomplete cerebral ischemia in rats. Rats were anesthetized with 1.4% isoflurane in air, and ischemia w...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.6.797
更新日期:1991-06-01 00:00:00
abstract::The goal of this study was to test the hypothesis that atherosclerosis alters responses of cerebral arteries and the ocular circulation to the activation in vivo of leukocytes and platelets. We measured blood flow to the brain and eye using microspheres and pressure in the cerebral microvessels of normal and atheroscl...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.6.790
更新日期:1991-06-01 00:00:00
abstract::To compare the diagnostic yields of transesophageal and transthoracic echocardiography in the detection of potential cardiac sources of embolism, 63 patients (mean +/- SD age 63 +/- 15 [range 18-87] years) with transient ischemic attacks or stroke underwent both procedures. Transthoracic echocardiography revealed a po...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.6.727
更新日期:1991-06-01 00:00:00
abstract::To clarify the nature of ischemic striatal dopamine release during the earliest periods of neuronal injury, we used chronoamperometry to measure dopamine levels every 60 seconds during various durations of ischemia in 32 gerbils. Catecholamine-selective electrodes were implanted into the brains of anesthetized gerbils...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.5.674
更新日期:1991-05-01 00:00:00
abstract::Leukoaraiosis quantified by computerized densitometric measurements of reduced Hounsfield numbers was correlated with local cerebral blood flow on the same computed tomographic images of 35 patients with multi-infarct dementia and 16 age-matched elderly normal volunteers. The ratio for area of frontal leukoaraiosis to...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.5.609
更新日期:1991-05-01 00:00:00
abstract::This study, in biologically bred hyperglycemic diabetic rats, examined the effect of a intravenous insulin infusion (1.5 units.hr-1) on blood, plasma, and brain glucose concentrations to determine their relationship during decreasing blood and plasma glucose levels. The data were compared to saline-treated diabetic ra...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.4.505
更新日期:1991-04-01 00:00:00
abstract::We studied a possible relation between stroke and an enhanced susceptibility to rupture of the arterial internal elastic lamina by comparing stroke-prone spontaneously hypertensive rats with spontaneously hypertensive rats, which have a very low incidence of stroke. We quantified interruptions in the internal elastic ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.4.510
更新日期:1991-04-01 00:00:00
abstract::Of 564 consecutive patients with transient ischemic attack, 350 (62%) had cranial computed tomography performed. Except for date of admission and smoking history, there were few differences between the patients evaluated with computed tomography and the 214 who were not. Cerebral infarcts were found in 59 (17%) of the...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.4.431
更新日期:1991-04-01 00:00:00
abstract::A 26-year-old woman had a peripartum venous thrombotic stroke involving the right parietal lobe. The initial thrombus was present only in the right channel of a congenitally bifurcated superior sagittal sinus. This diagnosis and subsequent thrombus extension were readily shown by magnetic resonance imaging in contrast...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.3.396
更新日期:1991-03-01 00:00:00
abstract::Little is known about outcome after cerebral infarction for different ethnic groups. Of 590 stroke patients hospitalized from 1983 to 1986 at the Neurological Institute, cerebral infarction over age 39 years occurred in 135 whites, 177 blacks, and 82 Hispanics. Outcome after cerebral infarction differed by ethnicity. ...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.3.305
更新日期:1991-03-01 00:00:00
abstract::The purpose of this study was to develop an animal model that could be used to test the ability of Doppler ultrasound to detect arterial emboli composed of materials that are often involved in cerebral emboli. Emboli introduced into the rabbit aorta via the left renal artery consisted of clotted whole blood, platelets...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.2.253
更新日期:1991-02-01 00:00:00
abstract::We compared 211 consecutive patients who had acute ischemic hemispheric stroke and atrial fibrillation with 837 consecutive patients who had stroke without atrial fibrillation. The atrial fibrillation group included a higher frequency of women, older subjects, and those with a severe neurologic deficit, abnormal compu...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.2.169
更新日期:1991-02-01 00:00:00
abstract::We assessed the potential of 2-MHz pulsed-wave transorbital Doppler ultrasonography to delineate the role of the ophthalmic artery as a source of collateral cerebral blood supply by comparing oculopneumoplethysmography, transorbital Doppler ultrasonography, periorbital continuous-wave Doppler ultrasonography, and tran...
journal_title:Stroke
pub_type: 杂志文章
doi:10.1161/01.str.22.1.31
更新日期:1991-01-01 00:00:00